DPCstruct | MC49538

Metacluster Properties and Pfam Annotations

Number of structural domains157
Mean domain length (aa)104 ± 21 aa
Standard deviation of domain lengths20.58
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.08
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)21.44
Pfam Score99.31
Assigned Pfam label(s) CL0361- PF18615

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A194RLD8 11-85 GFICRLCSEMHRVVLHIYGHEGIRLNISEKINKYLSINVSPSDPLPKTICNNCLERLENQHRLVMRIEQAANLLK
B4H6I7 6-99 QYSIHTVCRTCLSTLHDTMAYDLFLIPGLAKKLCVCTSLSVEQQDGFPKNLCFNCYAKLNELHDFQKLCVDSVQKFQDLVSSNAFTC…
B4IF79 61-164 None
A0A6J1WRV3 1-75 None
A0A2A4JUJ7 251-348 None
A0A5E4QCX7 2-106 None
A0A5E4QF13 3-72 None
A0A6J1WHU3 2-117 None
A0A7E5WT35 26-126 None
A0A1B0BMM4 5-100 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.