DPCstruct | MC49523

Metacluster Properties and Pfam Annotations

Number of structural domains190
Mean domain length (aa)148 ± 30 aa
Standard deviation of domain lengths29.84
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.60
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)22.45
Pfam Score72.79
Assigned Pfam label(s) CL0425- CL0163- PF06350- PF00374- PF00346

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q2WGE5 149-324 None
A0A8B0SGL1 49-168 None
A0A5Q2FGV8 588-729 None
A0A832AEM2 1-82 None
A0A1Q7JBZ6 464-633 None
A0A7Y3IVG6 54-199 None
A0A843CT04 211-380 None
A0A7W3IP99 265-418 None
A0A847AX87 37-182 None
A0A2K5UE23 150-264 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.