DPCstruct | MC49497

Metacluster Properties and Pfam Annotations

Number of structural domains456
Mean domain length (aa)131 ± 23 aa
Standard deviation of domain lengths22.88
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.87
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)18.91
Pfam Score53.80
Assigned Pfam label(s) CL0196- CL0263- CL0081- CL0229- PF19060

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q9EMA1 893-1013 None
A0A5J4WPJ5 41-161 None
A0A5J4WND0 3-117 None
A0A5J4WKH2 1-82 None
A0A5J4WCY0 528-635 None
A0A2J7Z8G4 80-177 None
A0A4Y5QMF0 334-509 None
A0A7T2Y962 14-151 None
A0A3P8KM67 25-164 None
A0A1X2GTD3 517-646 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.