DPCstruct | MC49497

Metacluster Properties and Pfam Annotations

Number of structural domains456
Mean domain length (aa)131 ± 23 aa
Standard deviation of domain lengths22.88
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.87
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)18.91
Pfam Score53.80
Assigned Pfam label(s) CL0196- CL0263- CL0081- CL0229- PF19060

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q6MVJ2 74-199 None
A0A661IT82 202-356 None
A2HS63 1-78 None
A0A2R7K7N7 13-171 None
A0A662EHX9 28-188 None
A0A5U6SP31 13-114 None
G2HDB7 107-245 None
A0A2A5DAF2 115-279 None
A0A1E4ZHQ6 55-170 None
A0A812TDD4 773-908 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.