DPCstruct | MC49497

Metacluster Properties and Pfam Annotations

Number of structural domains456
Mean domain length (aa)131 ± 23 aa
Standard deviation of domain lengths22.88
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.87
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)18.91
Pfam Score53.80
Assigned Pfam label(s) CL0196- CL0263- CL0081- CL0229- PF19060

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3E0E429 74-150 None
A0A1N6MWX8 4-188 None
A0A7C2V2X7 6-116 None
A0A373NS91 5-159 None
A0A168PSG2 52-160 None
R5AP17 49-175 None
A0A3N5EJM6 3-121 None
A0A359IP23 84-248 None
N2A9S1 247-412 None
A0A7V8LRT5 1-89 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.