DPCstruct | MC49497

Metacluster Properties and Pfam Annotations

Number of structural domains456
Mean domain length (aa)131 ± 23 aa
Standard deviation of domain lengths22.88
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.87
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)18.91
Pfam Score53.80
Assigned Pfam label(s) CL0196- CL0263- CL0081- CL0229- PF19060

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A084ACA5 2-107 EMKQIPDYPNYAVTKDGRVWSYNRNKFIKLRVSKENSVIVNLSFEGIRFRRNVARLVFIAFKGYEPEIVRHKDNNPTNNCLKNLEGI…
A0A0F0CGH1 28-156 IEPIAEDEVFVQLLDHKDSWISNYGRAVSFYNGKYFLTRKKINKDGEICYQLNRNVFDGRNWVWKKQVIEAWKLVVKEFTVNYDISN…
A0A2G5EAV0 184-356 None
A0A397S736 6-148 None
A0A1G7ZRW3 294-412 None
R1D6B8 13-165 None
R1D116 233-363 None
A0A7K0KJ81 7-123 None
A0A495SMJ8 41-194 None
A0A4V1BJ06 33-156 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.