DPCstruct | MC4949

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)137 ± 12 aa
Standard deviation of domain lengths12.20
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score72.79
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)38.19
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0L9TAQ2 1-124 MADVREQISGEGGPYAPVNWPEEGDVWRWKTGTKVTSSGKYYKHRSLHLPPRLFAILEEEERREKTSLTKVFKSKVTFTRYIERYFP…
A0A2K3PAR1 1-129 MAKNNRHNNDPTGLNLPPVAADQIGQGLPYAPINFPEQGDVWGWKTGKRLQPNGCFQDRYLYLPERLSSGSDSKDQHTFRSKLSVER…
A0A2Z6PHN7 1-120 None
A0A067G4M6 7-135 None
A0A6V7QYN8 13-147 None
Q94GQ3 229-359 None
A0A811N2P1 176-314 None
A0A7J9GJ54 52-201 None
A0A2Z6PFV2 1-140 None
A0A438F7D1 50-184 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.