DPCstruct | MC49481

Metacluster Properties and Pfam Annotations

Number of structural domains478
Mean domain length (aa)286 ± 66 aa
Standard deviation of domain lengths65.88
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score77.24
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)15.73
Pfam Score67.30
Assigned Pfam label(s) CL0023- CL0552- PF04526- PF04597- CL0209

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I6L8L2 9-212 LRRELLNTYEQLGKSGLPFLDDIGKVDVKFGLSLQLLKSIEQRGMGFNSIGTFKAIVKLSWVDTILRWDPEPPFDFQKIEISPDEIW…
A0A6V4BHT1 242-532 MLTVAIKVMKIIGIDEKAQTIDLILFIRMEWIMPDGSDPWIDWRDCLSWDTDQKPSKQLLPNGYTSETQTARVTFLQPLDLHHYPFD…
A0A5B7E0K6 473-829 None
A0A162MLG3 262-539 None
A0A7R9LJG4 1-195 None
A0A7S4A009 351-671 None
A0A3S0ZTC5 236-610 None
A0A554UPF3 62-339 None
A0A559QPM7 455-757 None
A0A6G0X8W7 148-473 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.