DPCstruct | MC49476

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)145 ± 23 aa
Standard deviation of domain lengths22.99
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.40
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.34
Pfam Score100.00
Assigned Pfam label(s) PF05947

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376UF21 1-151 MPVINLFPLEADPLHLSPLENEFLLRPMRIQDGHTEIYSVDNIISSRHTGSQAYVPFSSFRHRGGMLRHDAPERYYHTRVKRGPSGL…
A0A6J5DR42 67-207 VGLFCTPIVNLFEHTGAKLSRGEIVADYPLVPKPNRPAMRGIYSIDAVRDPSDGAVIPSLNAWGTRTGERFWLARHDSYAAIHHPGR…
A0A1W9F0S4 1-145 None
A0A2T5R345 495-620 None
A0A485C5I0 110-251 None
A0A2X1JM52 94-265 None
A0A090RV07 177-313 None
A0A4V1XRP7 480-600 None
A0A182T653 3-139 None
A0A3M5EDC7 179-327 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.