DPCstruct | MC49473

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)157 ± 32 aa
Standard deviation of domain lengths31.74
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score93.09
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)48.14
Pfam Score100.00
Assigned Pfam label(s) CL0103

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376UC30 1-147 MTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNPKGFGLLQLDRDFSHYQDIMGWYNKRPSLW…
A0A4P1B2Y6 240-379 TSMFLFGPNQPSPATNYRPALHDSNGLSILAGNGEWIWRPLNNPKHLAVSSYAMENPQGFGLLQRGRQFSRFEDLDDRYDLRPSAWI…
A0A844W8H0 82-182 None
A0A655X0X0 117-299 None
A0A3S4I022 171-250 None
A0A377E431 1-199 None
A0A6A5KY21 908-1070 None
A0A1W6ZIV4 377-570 None
A0A3M5YZ86 266-456 None
A0A7X3U039 274-454 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.