DPCstruct | MC4946

Metacluster Properties and Pfam Annotations

Number of structural domains132
Mean domain length (aa)121 ± 33 aa
Standard deviation of domain lengths33.28
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score85.61
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)26.54
Pfam Score100.00
Assigned Pfam label(s) PF00830

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H2AP56 44-172 PLYIPKKVAEFPDYKYGEPSVFKQSKKGLYGGSFIQFGHSISESKNKVKRRWLPNIVRKELWSEALNRRIRIKLTAKVLRTISKEGG…
A0A5A7PW12 37-166 RKVVMGRAHRGLYAGRHIQFGNRVSEDGGNKTRRSWKPNVQEKRLFSYVLDRHIRVKITTHTLRCIDKAGGIDEYLLKTPYHKMDTE…
A0A1Q9CDQ1 133-240 None
R7WIN1 26-127 None
A0A6I9YLS9 38-213 None
A0A0R4J8D7 80-192 None
M1W980 1-170 None
W7AMP2 91-170 None
L0B0N8 32-176 None
A0A5B6W6K5 1-110 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.