DPCstruct | MC49458

Metacluster Properties and Pfam Annotations

Number of structural domains61
Mean domain length (aa)134 ± 20 aa
Standard deviation of domain lengths19.63
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score89.54
Mean fraction of residues predicted as intrinsically disordered0.46
Mean length-normalized TM-Score0.41
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)30.39
Pfam Score100.00
Assigned Pfam label(s) PF05662

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376TPZ8 21-133 VVITNVANGAISAASSDAINGSQLYTTNKYIADALGGDAEVNADGTITAPTYTIANAEYNNVGDALDALDDNALLWDETANGGAGAY…
A0A2X3JBD7 68-208 RQIQNVAPGVLSINSTDAINGSQLFATNNQVSTNTGNIATNTANIAGNTTSINNLTNGTVGLVKQDQSTQAITVAGDKAGTSVNIAG…
A0A4V2BM93 1-106 None
A0A376TQR8 150-267 None
A0A6G3I549 297-442 None
E6Z0T9 3-132 None
A0A2P7ATL3 245-392 None
A0A2X3ILX9 48-198 None
A0A378MVA1 2-122 None
A0A6B2BII6 105-205 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.