DPCstruct | MC49426

Metacluster Properties and Pfam Annotations

Number of structural domains436
Mean domain length (aa)156 ± 29 aa
Standard deviation of domain lengths28.58
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score85.09
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.26
Pfam Score100.00
Assigned Pfam label(s) CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K1AWH1 2-93 VQEIAQKIIATAKEKKAQDIYFIPKEKSYELHMRVGDARCLVDSYEFDVLAAVISHFKFVAGMNVGEKRRSQLGSCDYQHGEKVSSL…
A0A522USZ0 275-411 KSNFPPIVKLVAMLVAEGSKARASDIHIEPRDKYVQIRFRVDGELQNVFKYQKDVHPSVVSRIKIISKLDITNRRTPQDGSTHVSFN…
A0A2W1TI54 538-709 None
A0A2H0AGS7 30-157 None
A0A7V3SYY2 353-520 None
A0A3M3TUV9 1-150 None
A0A812NCM1 68-218 None
D9UJE2 2-128 None
R6H5S4 91-227 None
A0A545SCT3 4-126 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.