DPCstruct | MC49410

Metacluster Properties and Pfam Annotations

Number of structural domains131
Mean domain length (aa)114 ± 21 aa
Standard deviation of domain lengths21.43
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score84.54
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)23.94
Pfam Score88.17
Assigned Pfam label(s) CL0633- PF03477- CL0339- CL0109

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W1QC65 9-125 CASCGRRYSTYERIEDVGLMVRKRDDSRDPFRREKVTAGILKATKNRPVSEFQVEELVDRVEERLRRKGPEVTSQQVGIEVLQQLRN…
A0A837DW88 12-98 MKRPESVIKRDGYRMPFASYKLKYIFSALGLEDQSDELICSVINKFGDQETVETAEIYDAVIATLKENNFDDEAESFITKHKVREEE
A0A7T9I1T0 8-101 None
A0A534I0M6 82-190 None
A0A1I7G7B7 14-149 None
E7GEL9 15-128 None
E7FHX6 2-97 None
X1D169 10-111 None
A0A523W638 24-123 None
A0A1V3WGW3 5-95 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.