DPCstruct | MC49407

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)119 ± 14 aa
Standard deviation of domain lengths14.35
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score90.82
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)34.71
Pfam Score96.67
Assigned Pfam label(s) PF02814- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A378A8S9 154-274 MVIKGGMINWALMGDPNASLPTPQPVFYRPMFGAMGKTLQDTCATFVSQAALDDGVKEKAGLERQVIAINNCRSVTKRDLVRNSATP…
A0A7W1K1Q3 1-102 VHGAEPTRYGPDWGATGAAPAALSTTFVSAAALDAGISRTLGTRRRLIAVRGTRSIRRDDLARNRTVPEIDVSPEDGTVTLDGQVLR…
A0A066YSE0 913-1033 None
A0A2I9DBP4 604-722 None
A0A7W4EXU7 1-86 None
A0A6A3B9W3 448-575 None
G8S4B6 403-521 None
A0A7K2XYX2 167-283 None
A0A377LS75 1-98 None
A0A8A3T7U5 439-569 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.