DPCstruct | MC49355

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)232 ± 38 aa
Standard deviation of domain lengths37.62
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.36
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.54
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3R6Z1Y5 143-367 SMSIDRLHDVIEASLYQLHNEDLTDTKRTFREAAADTLNDLVGHVRKSQADKTWTLVQKKHLSANIVLHDMMRTDPTTFESLIQLHT…
K3XCI8 92-333 NDENTALLSVLPDCLATADTKVVGVLNIVENATNPDHVIKKAVESPLAFNSVLSLKMAGSGREIAEIAQLHTINRVMCASKPSKDTT…
K3WT01 419-607 None
A0A067C840 597-897 None
G4ZY15 331-549 None
W2NW30 207-472 None
A0A225WYZ5 103-334 None
A0A662XRV8 194-394 None
K3WWY7 421-585 None
F0WFA2 133-442 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.