DPCstruct | MC49351

Metacluster Properties and Pfam Annotations

Number of structural domains74
Mean domain length (aa)333 ± 68 aa
Standard deviation of domain lengths67.94
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score74.02
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)22.87
Pfam Score85.25
Assigned Pfam label(s) PF08426- PF03348

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0M9VQ62 2-389 ATRVGYALLFCVDAIAAWISLTPSLARSIEEWTYKYVQVQCIQQETCVGVLAVHRITFALALFHVVLALLLVDVHDTRNPRATIQNG…
A0A3P6CWF0 41-398 KSLRARYIYGTIFLIINLCAWFIRDYAQKALTLLPHVSSCGPEGSHCFHTLGVLRVSLGCFIFFLIMFLSTWNTMKLHQAQNTWHSD…
A0A1P8B168 44-362 None
A0A3B5KZU3 46-431 None
Q6CAC8 2-388 None
A0A7J6TUH6 37-390 None
B4FY55 4-216 None
A0A446MGZ6 10-249 None
A0A091DTL2 171-570 None
A0A4Y7JPI8 31-400 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.