DPCstruct | MC49317

Metacluster Properties and Pfam Annotations

Number of structural domains70
Mean domain length (aa)371 ± 90 aa
Standard deviation of domain lengths90.00
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score87.36
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)31.67
Pfam Score86.79
Assigned Pfam label(s) CL0286- CL0279- CL0257

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A5LK68 78-340 EPIIGIETHVQLSTLTKAFCSCPYNYGSHPNTTICPICMGLPGALPVLNSKVIDFAVKLGLALNCKLAFNSKFDRKQYFYPDLPKGY…
A0A2H9TIM1 7-410 WTTVVGLEIHAQLASRHKLFSVAPNNCDAQLGTCCAPFDAAVPGALPLLNQECVDLALRAAIALRCNIRSRSFFDRKHYRYDDLPLG…
A0A0K9QJH8 70-288 None
A0A832ZXA5 5-421 None
A0A4Y7L8Y3 71-458 None
A0A2C9JR38 384-833 None
A0A0G0V2N4 2-402 None
A0A3T0Y475 498-962 None
L9JJ92 70-402 None
A0A536RDR0 294-699 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.