DPCstruct | MC49279

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)121 ± 20 aa
Standard deviation of domain lengths19.68
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.74
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)56.49
Pfam Score98.15
Assigned Pfam label(s) CL0105- CL0329

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T7PVQ2 29-149 SHRKFSAPRHGSKGFLPKKRSKRHRGKVKAFPKDDPSKPVHLTAFLGYKAGMTHVVREVDRPGSKVNKKEVVEAVTIIETPPMVCVG…
H0XV01 1-120 VFHRKFSAPRHECLSFLPQKCTSRHYGKVKSFPKDDLSRIHFKAFLGYKAGMTYIMWKVNRPGFKVNKKKVVEAITIVDILPRVDVG…
A0A212CLV5 36-150 None
A0A284QYX5 496-640 None
A0A146I0Z6 798-951 None
A0A6A6L103 112-205 None
A0A1I8I8V1 598-718 None
A0A0D9XPH0 292-413 None
A0A438MY39 737-887 None
A0A6P8SYI8 56-180 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.