DPCstruct | MC49225

Metacluster Properties and Pfam Annotations

Number of structural domains110
Mean domain length (aa)134 ± 30 aa
Standard deviation of domain lengths29.85
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score77.55
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)32.17
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y2LTC2 5-137 TGVICQIEKQVKRQLQWAACLLHFNELTFRHLFINLDGETTVPKSVSGPIGTQLSKCEKLPGVNFKSNECEISEIERKILSKDQQYL…
A0A6A4VIV0 100-241 LSQDPPRPVHWFVCQLHANELLLRAAFHFLDGSTTGPKSFSGPLGRAASGEVHQLGVATFRAVPGPLPDLPDQLVAELSSDQQLLYR…
A0A4Y2CQK4 3-114 None
T1FHT6 68-198 None
T1FBS3 5-177 None
A0A4Y2TJH5 19-147 None
A0A4Y2SYE2 17-157 None
A0A4Y2A4G7 5-112 None
A0A4Y2A0T2 11-141 None
A0A2G3APT4 12-112 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.