DPCstruct | MC49139

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)126 ± 10 aa
Standard deviation of domain lengths9.97
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score76.43
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)40.49
Pfam Score85.00
Assigned Pfam label(s) CL0065- CL0167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U0X9B4 119-235 TVDMSSEWRTFSNDDQGNDDPSRVGDGPNALLNGAQLNTSIAFGDGMKSRELHRAQNKANLDKGNKGLLQAYKQIGALCDGWQLPGT…
A0A835XP00 4-116 LIDDRAEWRTFADQEGLDPSRVGQALHPLLSNLDTTIGWERNDGGLSKAVNRAQARISNPDRKLVAAFREIGLKATLVRANADVEYR…
A0A0D2MAW9 47-162 None
A0A835LEQ5 36-150 None
A0A0U9HN80 951-1083 None
A0A7R9GCM7 335-467 None
A0A3S5A5D0 1-141 None
A0A182UBE7 234-367 None
A0A6G1NHF3 62-193 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.