DPCstruct | MC49063

Metacluster Properties and Pfam Annotations

Number of structural domains404
Mean domain length (aa)206 ± 46 aa
Standard deviation of domain lengths45.55
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score83.68
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)17.65
Pfam Score75.86
Assigned Pfam label(s) CL0023- CL0113- CL0110- PF09782- CL0163

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U9TRS6 1-115 MQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGSARVGYINNQYVLNPTTDELKESSLDLVVAGTAGAVLMVESEADVLS…
A0A7S3LLZ3 11-221 CGIRYKVGVPTVDAPMDGHVDVRVHLLPICSPKYESSRPGEESYVIAEFLNRTIEKGKLIDNSELCIQEGKSVYVLYVDIVCLNNDG…
A0A099P5E0 1-281 None
A0A654HS67 299-519 None
A0A1X6PH30 135-394 None
K8FF78 102-393 None
A0A1B0BK60 100-236 None
R9P1V7 2-222 None
C3ZZA1 11-153 None
A0A6S7G6B9 547-768 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.