DPCstruct | MC49022

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)366 ± 61 aa
Standard deviation of domain lengths61.37
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score71.34
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)22.46
Pfam Score84.09
Assigned Pfam label(s) CL0123- PF05499

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J7IHS5 6-414 KLRGSSLRARYEKRPLVNPAHPAGEKFRLWHWERCTSSSQRDASEAALPTNAKETALSVYPFARFNKRLETLRYTDEEYARYIASLP…
A0A7J6VW59 12-295 DYSFAKYNKSVDIVKYTDEEYEKYLTDPGWTKEETDQLFDLCGRFDLRFVVIADRFPSSRPVEELKSRYYAVSRAISAARTPTSGDV…
A0A6A4JTS0 2-251 None
A0A820UHK0 48-432 None
A0A4T0HCY0 20-385 None
A0A0V0QB85 60-456 None
G4T5D3 2-472 None
A0A803LEZ9 18-347 None
A0A1W0XAF6 463-853 None
A0A1Y2HG49 23-432 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.