DPCstruct | MC49010

Metacluster Properties and Pfam Annotations

Number of structural domains44
Mean domain length (aa)91 ± 12 aa
Standard deviation of domain lengths11.75
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score81.53
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)42.30
Pfam Score95.00
Assigned Pfam label(s) CL0072- CL0186- PF05997- PF10163

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P8YTI2 2-84 LYKTDQTLIMTGERERLKELLRTRLIECGWRDQIQMLCRDVVRERGVNNLKLDDLIAEVTAKGRALVPDSVKKELLQKIKVYL
A0A5P1E581 2-77 IESGEKEKLMELLRERLIECGWRDEMKALCRAYARKKGRNNVTVDDLIDVITPKGRASVPDSVKAELLQRIRSFLM
A0A3P8N6Z7 7-80 None
A0A6U3R3Q9 9-119 None
T1DG17 4-88 None
A0A4U5P0L7 1-94 None
A0A7S4E6Y5 12-114 None
A0A068UYL2 63-167 None
A0A1U8PC65 102-194 None
A0A0D8XTZ9 355-446 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.