DPCstruct | MC49009

Metacluster Properties and Pfam Annotations

Number of structural domains113
Mean domain length (aa)150 ± 29 aa
Standard deviation of domain lengths28.60
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.79
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)22.25
Pfam Score95.01
Assigned Pfam label(s) CL0007- PF04563- PF00542- PF04561

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P8YKU6 9-170 IFKDWQSDPKKLNEPIKAIEVKGLVKQHIDSYNYFINDEIKKIVKANEKVTSDADPLFYVKYLNVNVGTPDVEEAYNISKSTTPHEC…
A0A2G6C6V1 3-97 HQKDSWRNFVEDGLSEIFSEINPIDDYTGQKLALRFGSYRFEDPKTTDQFAKENNLTFEAPLHAMVELTNKVTGEVKEQEIYLGDYP…
A0A391NIM4 64-241 None
A0A1P8BFS9 16-184 None
A0A388KVJ8 162-353 None
Q8HTL6 81-225 None
A0A6C0JBE8 6-132 None
A0A086L503 150-300 None
A0A7J7IFM7 3-137 None
A0A4Q3JVX5 1-132 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.