DPCstruct | MC49008

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)77 ± 9 aa
Standard deviation of domain lengths8.81
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score87.57
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)45.75
Pfam Score98.00
Assigned Pfam label(s) CL0039- CL0340

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P8YIH2 92-159 RLKSLREPSKKMSKSDQDPKSRIELTDTPEAILEKCKKAVTDFTSKVTYDPVNRPGVANLLTIHSLFT
A0A833UMV0 24-91 RVMSLTDGLSKMSKSAPSDQSRINLLDSKDEIANKIKRCKTDAFTGLEFDNPERPECNNLLSIYQLMS
A0A5S6QL48 209-276 None
A0A6A5L2Z3 175-256 None
A0A377DC28 48-134 None
A0A194VM69 736-818 None
W9WXQ4 110-191 None
T5A6T9 1-80 None
A0A7S1XC53 38-123 None
A0A7Y1TWK6 17-95 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.