DPCstruct | MC49006

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)350 ± 80 aa
Standard deviation of domain lengths79.61
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score77.50
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)20.79
Pfam Score100.00
Assigned Pfam label(s) PF05478

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P8YHV4 85-420 VLLIWTLLLSGISCGCCGAENRAAPTLLTAVILMSVLSIALWGVALSALLIGGHGEVFICRPLYDEPEYRALTSLVDRPGVLFQNGG…
A0A6J8BPZ1 11-208 KLLLQNSSHSLSLKKILRDCEVGKSAYAAFELSNIIDISALTNYSGTLNVESQLDNIDVDLSNLEILTPNLTAQLNDLKLSADINFT…
T1KVV9 161-543 None
A0A834NBT9 66-454 None
A0A556TN07 48-479 None
B4H680 14-338 None
A0A0Q9XAN9 507-932 None
A0A498MS93 546-949 None
A0A7R9EDY7 352-675 None
A0A6P5U4B5 634-1069 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.