DPCstruct | MC49005

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)65 ± 5 aa
Standard deviation of domain lengths4.87
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score92.44
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)48.64
Pfam Score94.44
Assigned Pfam label(s) PF00082- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3CAX2 235-300 TWRDVQHLIAKTAKIPNPTEPGWNINAAGYHVHHRYGFGLLDAGLMVQQAACFQRAPPQRECTEEI
A0A2P8YHT4 2-62 QHIVVRTARPANLKSPDWKVNGVGRNVSHSFGYGLMDAYAMVKLARSWKTVPEQHKCEVSA
A0A0V0WHT1 51-112 None
A0A7R9QRG9 30-91 None
H3CMR1 198-259 None
A0A8B6BU46 380-447 None
A0A0G2KZR4 12-77 None
A0A7M3XJ53 30-89 None
A0A0B2VGR5 205-277 None
A0A7J8BTA4 12-77 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.