DPCstruct | MC49003

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)139 ± 11 aa
Standard deviation of domain lengths11.10
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score81.96
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)34.60
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P8YCK5 101-239 GPLEEMHLLPDPVFVLPTDGVTINTIASTATGRIFLGGRDGCLYEVAYQGACSWFGKRCKKLNHSTGTLSFLVPSFLNMAFSEEDPI…
A0A059JD43 114-236 VPIRGLDINVIASSDSTGRIFFAGSSDNDVYELTYQQEERWFQGRCSKVNHTTKSFTAFAPQFNLRNKPTEFVEQMVVDDSRNLLYT…
A0A3P7DVV5 1-129 None
A0A0M3K8X3 236-367 None
A0A7G2C0L5 1-134 None
S9TRY2 76-218 None
A0A4W3HDG0 26-169 None
A0A183I2J2 189-318 None
A0A183CX21 1-129 None
P38181 241-404 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.