DPCstruct | MC490

Metacluster Properties and Pfam Annotations

Number of structural domains152
Mean domain length (aa)247 ± 51 aa
Standard deviation of domain lengths50.52
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score73.80
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.30
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)14.53
Pfam Score98.48
Assigned Pfam label(s) CL0123- PF02946

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1C7LXV4 252-556 NSRQPNAYNAWSHHIAKEANEASQASPSNLLNLQQEKIDDYYDLTEEQWEQYVNELVDQRQSQSTSLRTTQRGRTQDVNNICGKIVD…
A0A286U957 32-283 SLDEFRHFAEREGRDFLQIRLSAARWHSKFLFEYEKQHNNANESNIQTSVKEQIEDVLTNVSNTLESLCEATSQHSFMLVVDPKDES…
A0A485P0Z2 25-239 None
A0A2I1EM79 527-785 None
E3JUE2 125-365 None
A0A5N4CXZ4 131-367 None
A0A2N5VIR5 124-370 None
A0A2N5VRY6 9-215 None
V2WQG4 3-270 None
M5FPI1 759-1009 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.