DPCstruct | MC48995

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)182 ± 26 aa
Standard deviation of domain lengths25.73
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score67.04
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)26.04
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C1GQW7 21-189 SHNMAAMALQKLQSRQLNLCKPIRRPYSCVKSCGEGYEECGSFPHCYNPTVGESCCTNGKYCPKGTFCTDSGCCPEGSSLADCNATE…
A0A7C8MQQ2 20-190 VSSSSVVAAQQEFWWSFKPNHTSDEGYDPSFEICGTSCDGCDRSAKQCFSSEFANICYQPDQGESCCKDQYGTACVDGFYCAYNDKA…
A0A420Y4A9 1-238 None
A0A0F2LRE7 191-415 None
A0A6G1FXH5 84-244 None
A0A6A5W857 34-187 None
A0A6A5U5P8 5-190 None
E5QYB5 14-171 None
M2V973 1-216 None
A0A0J9EKZ2 1-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.