DPCstruct | MC48953

Metacluster Properties and Pfam Annotations

Number of structural domains455
Mean domain length (aa)214 ± 43 aa
Standard deviation of domain lengths43.36
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.49
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)19.62
Pfam Score93.98
Assigned Pfam label(s) CL0023- CL0264- CL0187- PF11860- CL0155

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A498KG52 83-339 None
A0A375I2Q7 7-194 None
A0A7W1JDU3 90-304 None
A0A074Z7N9 334-620 None
A0A6B3NAQ5 303-497 None
A0A158HJZ6 833-1049 None
A0A4V6MSB2 153-280 None
A0A2N9J9P0 1-134 None
A0A1J5XBE7 20-213 None
A0A1J5WTU7 26-201 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.