DPCstruct | MC48953

Metacluster Properties and Pfam Annotations

Number of structural domains455
Mean domain length (aa)214 ± 43 aa
Standard deviation of domain lengths43.36
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.49
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)19.62
Pfam Score93.98
Assigned Pfam label(s) CL0023- CL0264- CL0187- PF11860- CL0155

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7K2LA92 5-168 FANTGSDTVKKQEAAAFLANVSHETGGLVYVVEQNTANYPHYCDSSQPYGCPAGQAAYYGRGPIQLSWNFNYKAAGDALGIDLLHNP…
A0A4U1BMN7 68-287 RPSVSSSDFVELTPPLLMRAVPKLRSQRVDDLCAALNEVLPRYQIVGTRRQAHFLAQVGHESMSFLATTENLNYSATALQSTFGKYF…
A0A1E7I3P6 103-367 None
A0A158BUG6 81-274 None
A0A2E4QVS9 85-292 None
A0A557QLR5 9-192 None
A0A423ES90 470-698 None
A0A418WDB1 193-382 None
N4X903 12-252 None
F4PK72 622-836 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.