DPCstruct | MC48898

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)70 ± 13 aa
Standard deviation of domain lengths13.39
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score84.47
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)33.95
Pfam Score88.46
Assigned Pfam label(s) CL0166- PF03123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A381ICZ8 1-66 MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKIEKIYYVQDHMQTKFLELLKNVS
U5PFJ4 2-50 YRILNPLNHNVALVRNDKGEELIVIGKGIVFGKKKGDLVPKEKVEKLQV
A0A2N6SPK0 1-74 None
A0A375I1N7 1-51 None
A0A6B9I1B9 1-74 None
A0A7U9R8D9 1-78 None
A0A0R1QEN1 1-54 None
D7UWU4 5-79 None
A0A1H8BAK2 1-75 None
R6QN42 1-68 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.