DPCstruct | MC48879

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)144 ± 29 aa
Standard deviation of domain lengths28.89
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score71.49
Mean fraction of residues predicted as intrinsically disordered0.45
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)28.40
Pfam Score100.00
Assigned Pfam label(s) CL0361

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T1FYM5 2-116 VAMEIIDEMALGLCFEIHRSCKRGLLFLDEMDAESQKLYEIVNIRGVDVFGQTFSAKKQYDCICPNCHRNLAASRFAPHLEKCMGMG…
Q5FC18 2-98 QPASLAGISCTIFENLLKDYTHELTQTVHKNAKLSLQKCPACNKHCRQYCTKPGYDIYGNSVQTPSNVPYYSCLMCKREIAASRYAA…
T1FN97 1-176 None
A0A5D2UU52 1-136 None
A0A5D3BBT0 252-366 None
R7QND3 112-318 None
A0A654HWH0 3-148 None
A0A2J8AH53 42-159 None
A0A3B5R668 11-163 None
A0A4Y2CET0 1-148 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.