DPCstruct | MC48853

Metacluster Properties and Pfam Annotations

Number of structural domains142
Mean domain length (aa)255 ± 51 aa
Standard deviation of domain lengths50.70
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.14
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)25.33
Pfam Score99.63
Assigned Pfam label(s) PF06985- PF09362

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A395IX96 6-244 FGFSMDYASTQKSTCSSCTVTKDLSNYWTPTLFYQAQNGSFIPVTQNGGVTVYYLQRSDPLDPEYANGLLAFPEGFRMVAGNPYLRS…
A0A7K1J1A2 4-165 LDNGQLITPVKSVAYYRAGVGVDPTTVVAFPPGLMMIAGDPMATEAQPTSVVAWSCGSGGMREELPPSCPDDRGLRIDITFPDCWDG…
A0A5N0UQR7 140-346 None
A0A2D8F847 77-344 None
A0A0M9VUW5 22-316 None
A0A2P4YMR6 7-282 None
A0A6G1HS81 6-238 None
Y0KIC6 326-582 None
A0A0D0TW39 209-522 None
Q2GX37 1-274 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.