DPCstruct | MC48846

Metacluster Properties and Pfam Annotations

Number of structural domains208
Mean domain length (aa)299 ± 75 aa
Standard deviation of domain lengths75.05
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score82.28
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)24.40
Pfam Score98.48
Assigned Pfam label(s) CL0023- PF17763- PF01237- CL0266- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A395IJD1 7-274 EKIAPQHKSAWFGFIKSVATFKGDLSTLTAPPFLLSPQSIVEFPTYWAEHPSFTLKWQHSTRDENGKKKGMKPLNPFLGECFMGSWE…
A0A0C4E4P1 3-213 EQLEYAHLLDSAARQKQARDRLLYVTAFAVSQFSSVRARERAIRKPFNPLLGETFELLRAEPEVPGGLRLLVEKVSHRPVRLALHAD…
A0A4Q2D557 1-251 None
A0A7C3KKD5 7-208 None
A0A090KZF9 338-647 None
A0A498LPU9 510-889 None
A0A7R9TX15 96-314 None
A0A267GH48 475-833 None
A0A369RYD4 746-1045 None
A0A369JGA0 256-499 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.