DPCstruct | MC4884

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)95 ± 7 aa
Standard deviation of domain lengths6.80
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score80.42
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)24.59
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4T0UP43 263-355 TRKVADCGAFDMEDLDGGFLLKVVANMKRDPEAKVRFGTSGNGFTPNYVISYGDGRTVCFAGCNHQTMPKGKMFSEKNLSGFFSRLD…
A0A525D8B4 92-181 SSIEWDESRVAHLSINYLQKVFTNMGDDGDKVFFSTSGKGIRPSYQIEFKNHDLAAFNGAAHSPLKKTFPPESDLISQPFTQGFIRS…
A0A2N5EAN7 1-93 None
A0A127P4W0 1-94 None
A0A853FW44 1-94 None
J3HVH6 64-153 None
A0A158EIX3 10-93 None
A0A158EFA0 3-99 None
A0A155ZV38 9-104 None
A0A4Q3LWA1 4-100 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.