DPCstruct | MC48757

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)123 ± 18 aa
Standard deviation of domain lengths17.63
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score80.07
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)23.40
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A068YD18 10-133 IEAERYLDEKRIPELLHNLSSLVVFNRPENPIEYMISILEKLKAAQHGRGENPFIFTLANAESIFHMLDPNMRGYVTFEQYKHGLET…
A0A3Q3X7A9 7-113 EDAVEYMRRHQVPELLENLSSMLFFCRPENPREFLLQQLEGGGVRGPHLFTSTNLDAVFRILDPSDQKYISFAQYKHALSTLGVRDI…
A0A388KNN0 76-213 None
A0A5B8MJK0 3-140 None
A0A817KY33 64-179 None
A0A1S8VXU2 23-143 None
A0A7S1KPF3 220-366 None
A0A1V9ZHC5 380-512 None
A0A814QPB9 71-184 None
A0A6S7HX58 2-92 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.