DPCstruct | MC48745

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)77 ± 8 aa
Standard deviation of domain lengths7.93
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score84.93
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)51.49
Pfam Score100.00
Assigned Pfam label(s) CL0188

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A821QCZ8 1-75 MSWEMQLNESLLEELYEWIDSLSLSRPKKIIERDFSDGILVAEIIHYYLPEFIDLNNYNAANSLEHKKLNWLIEY
G4YHY3 3-71 SVYVWVSQFAFSRPMKNPPRDFSDAVLLAEILAQLVPAWVQLHNYPSTLRFQQKLSNWETLNRKVLTRL
A0A667G2P6 1-92 None
H3GCM0 603-683 None
A0A2R7W4K2 26-116 None
A0A182JK29 1-86 None
A0A822E2K1 1-77 None
A0A818WCL0 1-76 None
U6KB70 31-113 None
A0A671ELC5 8-73 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.