DPCstruct | MC48696

Metacluster Properties and Pfam Annotations

Number of structural domains621
Mean domain length (aa)210 ± 51 aa
Standard deviation of domain lengths50.60
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score68.35
Mean fraction of residues predicted as intrinsically disordered0.44
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)15.49
Pfam Score96.24
Assigned Pfam label(s) CL0023- PF13868- CL0489- PF02944- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A182G3P2 9-212 KCVWSKDAVMALITSWSSKEHLYNTKHDLYKNKHARQHALSEICESLQAIMPGINIDDVKNKINNLRSQYSRELTKHRTSARSGTGT…
X1XLZ2 178-295 IDDNKTFWLEFIGLYHTFPELWKVKSEAYKNRIKKDAAYEKLVEKMKEIDPKANRDLVRAKINSLHTSYRRELKKVKSSQKSGAGAD…
A0A6L5CS24 17-254 None
A0A5E4PNY5 1-214 None
A0A5E4Q6X1 15-178 None
A0A482X2J3 7-290 None
A0A368FEZ3 11-254 None
H2B0S6 74-371 None
A0A1A9VWB9 186-363 None
A0A7E5WXL0 268-499 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.