DPCstruct | MC48673

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)282 ± 40 aa
Standard deviation of domain lengths39.90
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score76.53
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)29.66
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A366PWT0 281-594 MVERKFQIIDKYDFNRTYHGIEISEQWQAWETAHFFRVRSIIENPTVGARLISYGCDNGDGSSLNCTTTCSNATLMYNSPENLWNCM…
W9P726 1-335 MDQGIVRVINGGWMDGLTRDAVSRPDTSTILWETLYEPWNLFARLDKGDRVAVAEPVTLLRDVCSGHDSPGKNCSIVCNSSDDMFAS…
A0A5Q3DS03 4-206 None
J3P559 65-299 None
I1R976 1-287 None
A0A365N557 1-288 None
A0A2T4GVD2 2-270 None
A0A428SC72 1-282 None
C7ZG27 1-263 None
N1SAC3 1-355 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.