DPCstruct | MC48657

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)177 ± 18 aa
Standard deviation of domain lengths18.01
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score76.18
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)31.92
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C3DX03 21-191 QHFKGFNAMTDPPSKPKKHPEVDIYEALKEGPIVQFFEQAFEWEQMTYIYYPYFWGRKKNWIEVSKISDPDPLFMQFLNAGYARVVV…
A0A645AYW6 315-470 AAANQAAAEQEKENKEKKANFYRSTEANILKHNCIAYLLQSYAALGQTMSYDDGQQMQSFKMLFGDNLDNYTALAKFMEQAFEWQIM…
A0A3N1PPL4 658-821 None
A0A679HXP6 698-879 None
H1ZED2 6-147 None
A0A1B9Y6V9 415-578 None
A0A854GBM0 98-276 None
A0A849F990 24-181 None
A0A2V1B1R3 28-207 None
A0A371K8X9 361-540 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.