DPCstruct | MC48644

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)140 ± 19 aa
Standard deviation of domain lengths18.60
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score79.52
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)37.52
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U6L8X8 1-170 MWSRGMVVPEKFVSGTYAFKVVEDGKANCTEVVDGWKGAYTNFNGIPRAKAEKEELYTIPENVSFVAMYSPSADATASCRVVTCIKT…
A0A6P6RXA8 67-166 GTYAFTPISDSHTKDCCRCNEAIRTWKAAFTNFTGLPPSKDDGVDLYKDINNVSLVAMYNAQTPPVADCRIVKCTEKDTNALGVVCL…
U6JWX1 89-246 None
U6KBT9 63-202 None
U6KEP1 336-485 None
U6K7G4 117-265 None
U6K4C5 155-288 None
U6K063 1-143 None
U6JT10 130-241 None
U6N497 105-249 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.