DPCstruct | MC48548

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)117 ± 9 aa
Standard deviation of domain lengths8.73
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score87.60
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)33.75
Pfam Score100.00
Assigned Pfam label(s) CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J9E5H7 1-121 MVAEFEKYVKEGVSPEVRDEMLESKPGLNWDRFGFIVDMNHANMIFNRERNDACDEKDRQWKCLEAFRAHLQFLNERALKTGAEIYK…
A0A182ETG6 98-217 VAKFEKYVKEGSSLEVWDVMLESEPGPDWNRFGFIVDMDRANKIFNRKRDDAYDEGGRQFKCIEAFRAHLQFLNEKALKIADGIIEN…
A0A368FI50 154-274 None
A0A182T4T2 328-447 None
A0A6P7TYJ5 10-120 None
S9WDR6 134-248 None
A0A2H2JNG9 294-416 None
A0A811KD39 296-414 None
A0A0N4T450 310-430 None
A0A423T9T8 533-669 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.