DPCstruct | MC48543

Metacluster Properties and Pfam Annotations

Number of structural domains317
Mean domain length (aa)265 ± 59 aa
Standard deviation of domain lengths58.81
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score75.55
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)19.48
Pfam Score97.52
Assigned Pfam label(s) CL0220- PF05421- CL0030- CL0680- CL0144

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J9DWQ1 22-272 IAIHHVDNVTRVLFEAFDTHYITASHLRSSAATTLTDDFVEEEEYNWTFTTALFFTATLLTTIGYGNLVPVTFQGRMFCIVYALFGV…
A0A2I4AM18 9-216 TSCIIFYLFIGGAIFQILEERNWISARDTYIQKKEDLLRKYTCLTKENLNEILEVASQAAGQGVAITGEKHRNSWDWSNSVIFAATI…
A0A6A7FWM0 55-341 None
A0A0R3UMT3 7-224 None
A0A7S4P222 15-202 None
A0A0D8Y0P3 3-211 None
A0A0D8XMH2 12-256 None
G0PKR9 18-266 None
A0A7M5UVZ8 92-397 None
A0A6S7FGY4 368-620 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.