DPCstruct | MC48534

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)136 ± 16 aa
Standard deviation of domain lengths15.94
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score88.35
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)41.15
Pfam Score98.53
Assigned Pfam label(s) CL0016- PF18199

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J9B931 10-152 TAKRYAHGRTLLDLVDFHVMDYLIGNQDRHHYEAFSIFTNAPSYAIHLDNGRAFGRTDFDDDDILLPLKQCCVLRSSTFFTLLKYYR…
A0A6I9NX64 20-153 GTRLLDVMDMTIFDFLMGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDELSILVPLSQCCRVKKSTYVRLKLLAKEEFRLSVL…
F4WU70 97-227 None
A0A835NWR8 294-420 None
A0A356TK78 229-376 None
A0A6L5CHW6 241-368 None
A0A6J8E055 483-639 None
A0A7R8H1Y1 88-234 None
A0A4U5UJ14 172-308 None
A0A0Q9X9T4 577-717 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.