DPCstruct | MC4848

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)201 ± 28 aa
Standard deviation of domain lengths27.85
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score87.50
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)25.49
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E7PG07 255-482 IARVFEEEGLTTTGVVLIEEHAQRVKPPRMLAVPFFFGNALGEPDNPEYQHRVLQATFDLLDREQGPVLEQLPDDMVPDILMQGSET…
W4MBD2 1-229 MLAHTFESAGLTTVGLALVREHAERMKAPRMLWVPYPFGYVLGKPNDADLQHRILAAAFDLLSCEAGPVLADFPDEEPAPVLVQASA…
A0A2E5SZ82 6-206 None
A0A2D8Y1J0 2-176 None
A0A354VK31 2-176 None
A0A6L7NMR4 4-255 None
A0A355DGX5 2-175 None
A0A1F8MJZ9 1-173 None
A0A2E5KMT9 1-203 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.