DPCstruct | MC48448

Metacluster Properties and Pfam Annotations

Number of structural domains33
Mean domain length (aa)174 ± 16 aa
Standard deviation of domain lengths16.28
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score89.15
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)31.89
Pfam Score100.00
Assigned Pfam label(s) CL0126

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H2IS95 6-163 NLYIIPNDSPVCQLDATDAFKTLSETERKYAHFVAKASFDGALSVFLQVSPESAAIFYVLYKLFKAEPTGQLKAKALSVGFTEEEWM…
A0A0S7H9X8 2-187 VDSQYYLPNDIGISALDCREAFRLLSPQEKMYAHYLSRAAWYGGLVVLLQTSPESANIFVLLQRIFRKQTPEQLEQVAKAAGLSSED…
A0A2I2GN81 9-190 None
A0A4W3GLX6 2-163 None
A0A179H667 439-579 None
A0A5E4PZ76 1-194 None
A0A7R9Q1Z3 1-192 None
A0A2R6WYR9 22-184 None
A0A7R8A8G6 4-172 None
A0A183WSF4 160-315 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.