DPCstruct | MC48441

Metacluster Properties and Pfam Annotations

Number of structural domains163
Mean domain length (aa)109 ± 25 aa
Standard deviation of domain lengths24.63
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score84.26
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)23.41
Pfam Score100.00
Assigned Pfam label(s) PF01985

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A067KL54 1-114 MTEEERECFRKIGLKMHSSLVLGRRGVFDGVMEGLHQHWKHREVVKVITMQRIFSQVIRTAKFLEAESGGILVSVDKLKEGHAIIIY…
A0A838IKT3 16-107 SPKLSGKQRSHLRGLAHALKPIVLVGHKGVTEALIENLDAALLAHELVKVKVHEGDDIEEVATRLAKDSSAQLAQMIGHVLVYYRAH…
D7U8D5 101-235 None
A0A5D2L6H1 34-122 None
A0A7S4A840 182-285 None
A0A0B0PE08 9-125 None
A0A453E6D9 55-160 None
A0A022QTT1 93-208 None
A0A166C816 589-819 None
A0A834SDR5 74-193 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.